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pentobarbital will decrease the extent or effect of alprazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

There isn't any average intravenous dose of NEMBUTAL Sodium Solution (pentobarbital sodium injection) which might be relied on to make very similar consequences in numerous sufferers. The opportunity of overdose and respiratory depression is distant once the drug is injected slowly but surely in fractional doses.

Phenobarbital lowers the plasma amounts of dicumarol (identify previously utilized: bishydroxycoumarin) and brings about a lessen in click here anticoagulant exercise as calculated via the prothrombin time. Barbiturates can induce hepatic microsomal enzymes resulting in elevated metabolism and reduced anticoagulant response of oral anticoagulants (e.

pentobarbital will decrease the level or outcome of estradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

pentobarbital will lessen the level or effect of duvelisib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Coadministration with a powerful CYP3A inducer decreases duvelisib location under the curve (AUC), which can minimize duvelisib efficacy.

pentobarbital will lower the level or influence of lapatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

pentobarbital will minimize the extent or impact of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Powerful or moderate CYP3A4 inducers might boost fee of diazepam elimination; thus, efficacy of diazepam may be decreased.

pentobarbital will lower the level or result of conivaptan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

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